1885~ August Weissmann states generic information of a cell diminishes with each cell division.
1902~ Walter Sutton proves chromosomes hold generic information.
~Hans Spemann divides a Salamander embryo in two and shows early cells retain all the generic information necessary to create a new organism.
1928~ Hans Spemann performs first nuclear transfer experiment.
1938~ Hans Spemann proposes “fantastical experiment” of cloning higher organisms.
1944~ Oswald Avery discovers generic information is carried by the nucleic acids of cells.
1952~ Briggs and King clone tadpoles.
1953~ Watson and Crick find the structure of DNA.
1958~ F.C. Steward grows whole carrot plants from carrot root cells.
1962~ John Gurdon claims to have cloned frogs from adult cells.
1963~ J.B.S. Haldane coins the term “clone.”
1966~ Establishment of the complete generic code.
1967~ Enzyme DNA ligase isolated.
1969~ Shapiero and Beckwith isolate the first gene.
1970~ First restriction enzyme isolated.
1972~ Paul Berg creates the first recombinant DNA molecules.
1973~ Cohen and Boyer create first recombinant DNA organisms.
1977~ Karl Illmensee claims to have created mice with only one parent.
1978~ The release of David Rorvik’s book, In His Image: The
Cloning of a Man, sparks a worldwide debate on cloning
ethics.
1979~ Karl Illmensee makes claim to have cloned three mice.
1980~ U.S. Supreme Court rules live, human made organisms are
patentable material.
1983~ Kary B. Mullis develops the polymerase chain reaction
technique for rapid DNA synthesis.
~Solter and Mcgrath fuse a mouse embryo cell with an egg
without a nucleus, but fail to clone using their technique.
1984~ Steen Willadsen clones sheep from embryo cells.
1985~ Steen Willadsen joins Grenada Genetics to commercially
clone cattle.
1986~ Steen Willadsen clones cattle from differentiated cells.
~First, Prather, and Eyestone clone a cow from embryo
cells.
1990~Human Genome Project begins
1995~Wilmut and Campbell clone sheep form differentiated cells.
1996~Dolly, the first animal cloned from adult cells, is born.
1997~Presidents Bill Clinton proposes a five year moratorium on cloning.
~Richard Seed announces his plans to clone a human
~Wilmut and Campbell create a Polly, a cloned sheep with an interested human gene.
1998~Teruhiko Wakayama creates three generations of genetically identical cloned mice.